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DisLocate is a method based on Grammatical-Restrained Hidden Conditional Random Fields (GRHCRFs) and Support Vector Regression (SVR) for the prediction of cysteine connectivity patterns in a protein chain. The method takes advantage of the protein subcellular localization as predicted by the BaCelLo predictor.
For details see: Savojardo, Fariselli, Alhamdoosh, Martelli, Pierleoni, and Casadio (2011) Improving the prediction of disulfide bonds in Eukaryotes with machine learning methods and protein subcellular localization, Bioinformatics, 27(16), 2224-2230..